Post-disaster support is critical for responders’ well-being who navigate the physical, mental, and emotional challenges of crisis intervention. The January 2025 Eaton Fire destroyed structures and disproportionately impacted Black and Latino neighborhoods. AltaMed deployed approximately 230 staff members to serve as frontline responders, providing medical and psychosocial support to evacuees at the Pasadena Convention Center. AltaMed frontline responders were invited to participate in a four-phase support initiative that included on-site peer-led debriefings, a needs and experiences survey, resilience-building workshops, and formal recognition of their contributions. A mixed-methods analysis was conducted on quantitative and qualitative survey data to assess well-being. Survey participants (n = 113) were highly motivated by community service, with 93% reporting a desire to contribute during crisis response. In addition, 53% identified the emotional impact as challenging, and 56% expressed interest in additional training. Peer support and reflection activities were cited as protective factors. Responders requested additional trauma-informed resources and infection prevention training. AltaMed’s support initiative successfully addressed the stressors of disaster response. Structured recognition, resilience-building, and professional development can promote long-term workforce well-being. These findings offer scalable strategies for Federally Qualified Health Centers and health systems supporting frontline workers during emergencies exacerbated by climate change and systemic disparities.